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Clinical Study
Title: HYDROTHERAPY COMPARED WITH PEG-ES LAVAGE AND AQUEOUS SODIUM PHOSPHATE AS
BOWEL PREPARATION FOR ELECTIVE COLONOSCOPY: A PROSPECTIVE, RANDOMIZED, SINGLE
BLINDED TRAIL.
Joseph J. Fiorito, MD, Joan A Culpepper-Morgan, MD, Scott G. Estabrook, MD,
Patricia Scofield, LPN, Victor Usatii, MD and Jodi Cuomo, RpH2.
Gastroenterology, Danbury Hospital, Danbury, CT United States.
Purpose: Hydrotherapy is a method of colon cleansing using constant warm water
lavage using a contained temperature and pressure controlled device administered
by a trained technician. The aim of this study was to compare the efficacy and
patient acceptance of same-day hydrotherapy (HYDRO) with polyethylene
glycol-electrolyte lavage (PEG-ES) and aqueous sodium phosphate (ASP) in
patients undergoing elective colonoscopy.
Methods: Consecutive outpatients referred for elective colonoscopy were randomly
assigned to receive 4 L PEG-ES (n=55), two doses of aqueous sodium phosphate
(n=52), or same day hydrotherapy (n=53), as bowel preparation. The endoscopists
were blinded to the method of preparation. The overall quality of the colon
cleansing was evaluated with respect to the adequacy of visualization of the
right, transverse, and left colon. Patients were asked to rate the preparation
with respect to ease, convenience, and comfort using structured, validated
questionnaire. Results were analyzed using the chi square test.
Results: Endoscopists rated the quality of colon cleansing as good for the
right: 62% ASP, 49% PEG-ES, and 92% HYDRO (p<0.001). For the transverse colon:
80% Asp, 63% PEG-ES, and 100% HYDRO (p<0.001). For the left colon: 84% ASP, 67%
PEG-ES, and 98% HYDRO (p<0.001). Patients rated the preparations as easy: 87%
ASP, 56% PEG-ES, 96% HYDRO (p<0.001). Patients rated convenience: 61% ASP, 79%
PEG-ES, and 98% HYDRO (p<0.001). Patients rated for comfort: 71% ASP, 36%
PEG-ES, and 94% HYDRO (p<0.001). Patients were asked if they wanted a different
preparation for the next colonoscopy: 48% ASP, 60% PEG-ES, and 4% HYDRO
(p<0.001).
Conclusion: The quality of colon cleansing, overall tolerance, comfort, and
convenience were significantly better for HYDRO. In this study ASP was better
than PEG-ES for the same parameters. Hydrotherapy should be further investigated
as a viable alternative to PEG-ES and ASP for bowel preparation prior to
colonoscopy.
For further information contact
joseph.fiorito@danhosp.org
Abstract Number: 751814
Primary Author: Joseph Fiorito
Department/Institute: Gastroenterology, Danbury Hospital
Address: 24 Hospital Ave
City/State/Zip/Country: Danbury, CT, 06810, United States
Phone: 203-707-7506 Fax: 203-796-7974 E-Mail: joseph.fiorito@danhosp.org
Awards: No Award Selected
Abstract Categories: 11 Endoscopy
Presentation Preference: Either oral or poster only
ACG Research Grant: No
Key Words: Colonoscopy, cathartics, colon preparation.
*Manufacturer’s note: The equipment used in this study
was the Toxygen Model BSC-UV, a “closed system” manufactured by Dotolo Research
Corp. The Dotolo Colon Irrigation system has been cleared by the FDA for the
intended use as described in this study.
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